Our Science

Medicine reacts. We test for answers.

Most labs tell you whether you're sick. Zaro tells you what's developing, what's at the root, and how your biology is aging, so you can act years before a diagnosis.

The Cascade Model

No other testing platform offers all three tiers of the cascade. Each level answers a fundamentally different question about your health.

SurfaceHas something already gone wrong?
$149
SignalIs something developing?
$249
SourceWhat root causes?
$399
Surface → Signal → Source: deeper understanding at each level

Has something already gone wrong?

Surface

Body Systems Covered

Heart & Vessels
Metabolic
Liver
Blood Health
Thyroid
Kidneys
Electrolytes
Nutrients

The Science

Surface testing captures what has already crossed clinical thresholds. These are the markers standard medicine looks at during a routine physical, but that most people never get done as a full panel — the red flags that, caught early, prevent the most common causes of preventable death: heart disease, type 2 diabetes, thyroid dysfunction and anemia.

Who It's For

Anyone who has never had comprehensive bloodwork done, adults over 25 who want a baseline, or anyone who has not had labs in over two years.

Biomarkers Included

Metabolic Core

  • Comprehensive Metabolic Panel — glucose, BUN, creatinine, eGFR, BUN/creatinine ratio, sodium, potassium, chloride, CO₂, calcium, total protein, albumin, globulin, A/G ratio, total bilirubin, ALP, AST, ALT (18 values)
  • CBC with Differential and Platelets — WBC, RBC, hemoglobin, hematocrit, MCV, MCH, MCHC, RDW, platelets, MPV, plus neutrophils, lymphocytes, monocytes, eosinophils and basophils as both percentage and absolute count (20 values)
  • HbA1c (glycated hemoglobin)
  • Fasting insulin
  • Uric acid

Heart & Lipids

  • Lipid Panel with Reflex to Direct LDL — total cholesterol, LDL, HDL, triglycerides, non-HDL cholesterol, total/HDL ratio (6 values)
  • hs-CRP (high-sensitivity C-reactive protein)

Advanced Cardiometabolic

  • ApoB (apolipoprotein B)

Thyroid

  • TSH (thyroid stimulating hormone)

Nutrients

  • Vitamin D (25-OH)
  • Ferritin

Urinalysis

  • Complete Urinalysis with Microscopy and Reflex to Culture — color, appearance, specific gravity, pH, protein, glucose, ketones, occult blood, bilirubin, nitrite, leukocyte esterase, plus WBC and RBC per high-power field (13 values)
✓Comprehensive metabolic panel and full CBC with differential
✓ApoB — the cardiovascular risk marker most annual physicals skip
✓Complete urinalysis with microscopy and reflex to culture
✓FSA/HSA eligible
✓Results in 5–7 business days
Most Popular

Is something developing?

Signal

IncludesEverything in Surface is included in this panel.

Body Systems Covered

Heart & Vessels
Metabolic
Liver
Blood Health
Thyroid
Kidneys
Electrolytes
Nutrients
Hormones
Stress & Adrenal

The Science

Signal markers are the early-warning system of preventive medicine. Where Surface markers respond to disease that has already developed, these detect the conditions that lead to it. Fasting insulin rises years before HbA1c signals pre-diabetes, and NMR fractionation finds dangerous particle patterns a standard lipid panel reports as normal.

Who It's For

Health optimizers, athletes, anyone with a family history of cardiovascular or metabolic disease, and anyone who has done Surface and wants to go deeper.

What Signal Adds

Advanced Cardiometabolic

  • Lipoprotein(a) — inherited cardiovascular risk
  • Lipoprotein Fractionation by NMR — LDL-P, small LDL-P, LDL peak size, HDL-P, HDL peak size, large VLDL-P, VLDL peak size (7 values)
  • Homocysteine

Hormones

  • Testosterone — total, free and bioavailable, with SHBG, by mass spectrometry (4 values) — men
  • DHEA-S (dehydroepiandrosterone sulfate) — men
  • Estradiol (E2) — women
  • LH (luteinizing hormone) — women
  • FSH (follicle stimulating hormone) — women
  • Progesterone — women
  • Cortisol, AM — adrenal function

Extended Thyroid

  • Free T3 (free triiodothyronine)
  • Free T4 (free thyroxine)

Nutrients

  • Vitamin B12
  • Iron, TIBC and Ferritin Panel — iron, total iron-binding capacity, % saturation (3 values)
  • Magnesium

Metabolic Depth

  • Folate, serum
  • Zinc
  • GGT (gamma-glutamyl transferase)

Advanced Kidney

  • Albumin, Random Urine with Creatinine — urine albumin, urine creatinine, albumin/creatinine ratio (3 values)
✓Everything in Surface, plus 32 markers
✓NMR lipoprotein fractionation — particle number and size, not just cholesterol mass
✓Sex-specific hormone panel plus morning cortisol
✓Urine albumin/creatinine ratio — the earliest detectable sign of kidney stress
✓Lp(a) — inherited cardiovascular risk carried by roughly 1 in 5 people
✓FSA/HSA eligible
✓Results in 5–7 business days
Most Comprehensive

What root causes?

Source

IncludesEverything in Signal is included in this panel.

Body Systems Covered

Heart & Vessels
Metabolic
Liver
Blood Health
Thyroid
Kidneys
Electrolytes
Nutrients
Hormones
Stress & Adrenal
Brain & Cognition
Immune

The Science

Source reaches the upstream causes Signal does not capture: autoimmune thyroid activity, systemic inflammatory load, coagulation risk and the omega-3 status that shapes how you age. It is also the tier that unlocks Biological Age (PhenoAge) and Heart Age (AHA PREVENT), two independent reads on how your biology is ageing relative to your years.

Who It's For

Longevity-focused members, anyone with chronic fatigue, hormonal symptoms or unresolved issues, and anyone who has completed Signal and wants root causes.

What Source Adds

Advanced Cardiometabolic

  • Fibrinogen activity — coagulation and inflammation risk
  • OmegaCheck — EPA, DPA, DHA, omega-3 total, omega-6 total, arachidonic acid, linoleic acid, omega-6:omega-3 ratio, AA/EPA ratio (9 values)

Extended Thyroid

  • TPO antibodies (thyroid peroxidase)
  • Thyroglobulin antibodies

Autoimmune & Inflammation

  • ESR (erythrocyte sedimentation rate)

Cognitive Risk

  • Vitamin B1 (thiamine), whole blood by LC/MS/MS

Metabolic Depth

  • HOMA-IR — insulin resistance index, calculated from fasting glucose and insulin
✓Everything in Signal, plus 15 markers
✓TPO and thyroglobulin antibodies — detects autoimmune thyroid disease
✓Fibrinogen — cardiovascular risk independent of LDL
✓OmegaCheck — the full omega-3 and omega-6 fatty acid profile
✓ESR — systemic inflammation beyond hs-CRP
✓Unlocks Biological Age (PhenoAge) and Heart Age (AHA PREVENT)
✓FSA/HSA eligible
✓Results in 5–7 business days

Two ages. One clock.

Zaro calculates your Biological Age (PhenoAge), reflecting how old your body actually is based on blood chemistry, and your Heart Age using the AHA PREVENT model. Is your biology aging faster or slower than your birthday suggests?

Chronological Age

38
335 YRS YOUNGER

Biological Age

PhenoAge Model

413 YRS OLDER

Heart Age

AHA PREVENT

Example output · your results will reflect your actual blood data

Zaro Score

A living health score, built on three pillars

Zaro synthesizes bloodwork, wearable signals, and lifestyle into a single score out of 100. It updates continuously and adapts to whatever data you have, no wearable required to get started.

78/ 100Strong
Layer 1 · From your bloodwork
Clinical Foundation
PhenoAge10-yr CV Risk30-yr CV Risk

Score Bands

Optimal90–100
Strong75–89
Moderate60–74
At-Risk40–59
Critical<40
Layer 2 · From Apple Health & wearables
Daily Performance
VO2 MaxHeart RateHRVSleep
Score out of 10030-day trendBiological age
Layer 3 · From weekly check-ins
Lifestyle
ExerciseNutritionStressHabits

Adaptive weighting

Score adapts automatically as you add data

Full data

Labs + wearable + lifestyle

ClinicalPerformanceLifestyle

No wearable

Labs re-weighted with lifestyle

ClinicalLifestyle

Labs only

Biomarker Score shown

Clinical Foundation

Start knowing your body.

Choose a panel, schedule your blood draw, and get answers that actually explain what is happening inside your body.